MOTS-C 10mg Mitochondrial-Derived Research Peptide

MOTS-C 10mg is a lyophilized preparation of a 16-amino-acid peptide that is unusual in its origin: unlike the great majority of peptides in this catalog, MOTS-c is encoded within the mitochondrial genome rather than the nuclear one, in a short open reading frame located in the 12S ribosomal RNA region.

Why the origin matters

That genomic location is the reason MOTS-c attracts research attention out of proportion to its size. Its discovery contributed to a broader reassessment of the mitochondrion as a signaling organelle that issues its own peptide messages, rather than purely as a site of energy production. Peptides of this class are studied under the heading of mitonuclear communication — the question of how the two genomes in a eukaryotic cell coordinate.

Laboratory interest commonly includes cellular metabolic regulation, mitochondrial stress-response signaling, metabolic homeostasis models in cultured systems, and comparative analysis alongside other mitochondrial-derived peptides. Its short sequence also makes it a tractable subject for synthesis and structure-function work, where individual residues can be varied and the resulting analogs compared.

Format

The 10mg label strength suits cell-culture scale work, where the quantities required per experiment are modest and a single vial supports a full concentration series with material remaining for repeat runs.

Specifications

• Compound: MOTS-c (mitochondrial-derived peptide)
• Sequence length: 16 amino acids
• Label strength: 10mg
• Format: Lyophilized powder
• Intended use: Laboratory research only

Storage and handling

Store the sealed vial cool, dry and away from light, retaining the lyophilized state until required. Short peptides are generally robust as dry powder and considerably less so in solution. Record the lot identifier where results will be compared across batches.

Supplied for research identification and catalog purposes only. No clinical, diagnostic, therapeutic or usage claims are made or implied.

Research Use Only: This product is sold strictly for laboratory research purposes. Not for human or veterinary use. Not for diagnostic, therapeutic, food, cosmetic, or household applications.